Francesca’s signature sandwich, this is a riff on the muffuletta, but combines ham, roast beef, provolone, Swiss, and coleslaw on a muffaletta bun with Russian dressing as opposed to the normal components. The winning combo isn’t the only sandwich worth trying on the Lakeview deli and restaurant’s menu — the classic Club is just as it should be, and hits the spot.

Meat Mama Leighann Smith is one badass butcher. Thankfully her fans can look forward to Piece of Meat reopening Oct. 29 — just know she’s not playing about the mask, and she has knives. The deli is open Thursday through Monday, 11 a.m. to 7 p.m., the kitchen 11 a.m. to 5 p.m. There’s outside seating for ravaging sandwiches like the swoon-worthy smoked brisket with pickled red onions and horseradish mayo; the smoked tri-tip cheesesteak; the hot pastrami...and on.

The same great kitchen that used to be in the back of Siberia is on St. Bernard Avenue with a killer menu of salads, Eastern European blinis and outstanding sandwiches. Get the Green Room’s beet reuben for a real mouth surprise, roasted beets topped with braised cabbage, Swiss and Russian dressing on toasted buttered rye. There’s a version with corned beef too, equally good.

Besides addictively good pies and cakes, Chaya Conrad’s Bywater Bakery offers hearty sandwich specials daily, embraced by Conrad’s wonderful multi-grain or country white bread. There’s always a hefty BLT; love the lemon caper tuna salad, and sometimes, on a lucky day, a Bywater cheesesteak.

This family and dog friendly Bywater biergarten is so welcoming, with its picnic tables outside and area for the kiddos to romp. Open Thursday through Sunday, 1 to 7 p.m., Bratz Y’All! dishes terrific sausage sandwiches with names like the Berliner, a beauty of a grilled smoked pork link topped with fried onions and apple curry ketchup. The schnitzel sandwich, choice of fried chicken or pork cutlet, is slathered with crawfish remoulade slaw on a muffaletta bun, and most excellent.

No surprise that one of the best cubanos in town is at Manolito, Chris Hannah’s Cuban themed bar and cocktail lounge on Dumaine in the Quarter. A tribute to Havana’s El Floridita, the bar where Ernest Hemingway often sat, stewed and pickled, Manolito’s Cuban sandwich is a thing of beauty, sandwich bread stuffed with mojo pork, ham, swiss, house made pickles, mayo and mustard. Get any frozen drink and if the guava daiquiri is on the menu get two.

Sylvain is a swell bistro with a smart menu that includes fresh pastas and shrimp and grits with a smoked tomato brodo. But, its fried chicken sandwich is the bomb. Revel in the perfectly fried thigh with hot sauce on a just right brioche bun. Don’t even get started on the burger....

Ajun Cajun’s garlicky rib eye sandwich, a festival favorite, is love at first bite. Garlicky grilled steak arrives piled high on a toasted Dung Phuong roll, soy marinated bites of carrot and cucumber adding crunch under a slathering of gooey melted mozzarella cheese. Doesn’t get any better. Ok, technically they call it a po’boy, but it’s anything but traditional. Get extra napkins.

Gracious Bakery’s ciabatta will make any sandwich great — seriously, put anything on there. But the local bakery with three locations also has an excellent chicken salad, set off by pickled onions and greens that make for a winning combo. The toasted Black Forest ham sandwich is also excellent, as is the hot, reuben-style turkey.

New York style deli rocks the house at Stein’s, always served on Jewish rye, although a bagel is also an option. Can’t go wrong with the corned beef special with cole slaw and Russian dressing (get a little extra on the side), then again the tuna melt is damn good. There’s plenty that’s Italian too — order the mumbler because it’s fun to say, and even more fun to eat: ciabatta piled with prosciutto, taleggio, and arugula drizzled with aged balsamic.

Mason Hereford created national buzz when he opened his sly sandwich shop Turkey and the Wolf a few years back. And with good reason; it’s fun to eat combos like Leighann’s baloney, fried, layered with potato chips and hot mustard on toast. The collard green melt with cherry peppers is a winner, same goes for the smoked turkey with cranberry sauce, mayo, and aged cheddar.

If it’s a European train stop-style sandwich you’re after, look no further than Uptown bakery La Boulangerie, and its delectable menu of sandwiches served on crusty baguette or croissant. Le Parisien is a classic — butcher ham, salted butter, Comté cheese, and cornichons on baguette. The chicken salad sandwich and smoked salmon sandwich, as well as the turkey, all compete with the ham as the best on the menu.